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I buy off the web. I grind up a 500mg pill and dissolve in RODI water and dose daily with the skimmer off for a week or so. I forget the exact dillution. There is a long thread on it on R2R, better reading that then winging it.
I dont leave the skimmer off, I set it to off for a few hours after dosing. Carbon should be off too if you run it. I'd also take any oxydator out until finished (I'm not sure if this would effect it, but I take it out when using just in case).